To evaluate the economic backbone of aquaponic farms, we need to dive in: capital/investment cost (building the system, setup the operation logistics, etc.) operational cost; profitability of the operation; aquaponics is profitable when it is done to a specific scale. investment cost is relatively high which is the main drawback of aquaponics.. In aquaponic systems water that circulates is suitable for any crop as there are no additives and chemicals in it and the plants are taking only what they need. this is also called “poly crop” system. aquaponics is most productive and profitable when we choose the best growing system for specific crops..